IMM250H1 Study Guide - Midterm Guide: Edward Jenner, Variolation, Cowpox
UNIVERSITY OF TORONTO
Faculty of Arts and Science
Midterm Exam, Winter 2017
IMM250H1S
Wednesday, March 1st, 2017
Duration - 2 hours
No aids allowed. Please use pencil.
After completing this exam,
you may NOT take the exam paper with you.
This test consists of a total of 40 multiple-choice questions, and is
worth 30% of the final course grade
BE SURE TO COMPLETE
YOUR NAME AND STUDENT NUMBER
ON THE SCANTRON SHEET
!
2!
Choose the one best or most appropriate answer
!
Dr.$Philpott$
1.!What!is!the!crucial!point!of!the!landmark!experiment!performed!by!Edward!
Jenner!on!a!young!boy?!
A. He!discovered!how!to!distinguish!mild!smallpox!from!virulent!smallpox!!
B. He!performed!for!the!first!time!a!pioneering!form!of!vaccination!called!
variolation!
C. He!discovered!a!route!of!variolation!which!would!not!result!in!overt!disease!
D. He!proved!that!a!previous!exposure!to!cowpox!can!protect!from!smallpox!
infection!
Ans.!D!
2.!The!scientist!who!first!developed!a!technique!to!grow!pure!cultures!of!bacteria!
was:!
A. Robert!Koch!
B. Lady!Mary!Wortley!!
C. Ilya!Metchnikoff!
D. Paul!Ehrlich!
Ans.!A!
3.!Charles!Janeway!revived!the!interest!of!immunologists!for!innate!immunity!in!a!
period!dominated!by!research!in!adaptive!immunity.!He!proposed!for!the!first!time:!
A. The!existence!of!antigen!presenting!cells!
B. That!all!phagocytes!can!act!as!antigen!presenting!cells!to!induce!an!adaptive!
response!
C. That!adaptive!responses!would!not!be!triggered!in!the!absence!of!an!innate!
response!
D. The!clonal!selection!hypothesis!!
Ans.!C!
4.!Which!of!the!following!cell!types!can!kill!microbes!intracellularly?!
A. Mast!cells!
B. Neutrophils!
C. B!cells!
D. All!of!the!above!
Ans.!B!
5.!Which!of!the!following!best!defines!opportunistic!microorganisms?!
A. Microorganisms!that!take!residence!in!a!host!without!causing!disease!!
B. Microorganisms!that!cause!chronic!infections!
Document Summary
After completing this exam, you may not take the exam paper with you. This test consists of a total of 40 multiple-choice questions, and is worth 30% of the final course grade. Choose the one best or most appropriate answer. Dr. philpott: what is the crucial point of the landmark experiment performed by edward. D: the scientist who first developed a technique to grow pure cultures of bacteria was, robert koch, lady mary wortley, ilya metchnikoff, paul ehrlich. A: charles janeway revived the interest of immunologists for innate immunity in a period dominated by research in adaptive immunity. C: which of the following cell types can kill microbes intracellularly, mast cells, neutrophils, b cells, all of the above. B: which of the following best defines opportunistic microorganisms, microorganisms that take residence in a host without causing disease, microorganisms that cause chronic infections.
