PHYL 1010Y Chapter Notes -Hyperventilation, Hypoventilation, Alkalosis

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13 Mar 2014
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Buffers: helps body cope with changes in ph, moderates but does not prevent changes in ph by combining with or releasing h, adding acid to solution in presence of buffer moderates ph change/makes it unnoticeable, buffers in the body include, hco3 in ecf, proteins, hemoglobin & phosphates in cells, phosphates, ammonia in urine ph changes, changes in the body"s ratio of hco3/pco2 determines ph changes according to the henderson . Pathway i: na+ h+ antiport secretes h, h+ secreted from proximal tubule into lumen in exchange for na, h+ in filtrate combines with filtered hco3 to form co2 in the lumen, co2 diffuses into cell & combines with water to form h+ and hco3 in the cytoplasm, h+ is secreted again & excreted, h+ created in step 3 is secreted, replacing the h+ that combined with filtered hco3 in step 2, hco3 is reabsorbed. 4 (cid:226) (cid:226) (cid:226) (cid:226) (cid:226) (cid:226) (cid:226)

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