PSYC 211 Chapter Notes - Chapter 5: Confocal Microscopy, Scanning Electron Microscope, Transmission Electron Microscopy
8 Sep 2016
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Chapter5: methods and strategies of research (following the l-dopa treatment for patients in chap4) Symptoms of parkinsonism, whether from parkison"s disease or the toxic effects of mptp, are caused by the lack of dopamine in the caudate nucleus and putamen. As of now there is no way to induce the brain to grow new dopaminergic neurons but dopamine-secreting neurons can be introduced into the caudate nucleus and putamen. Because the implanted neurons must not trigger the recipient"s immune system, the only source is aborted human fetuses. The dopaminergic neurons were removed from the substantia nigra of fetal brains. Experimental ablation: the removal or destruction of a portion of the brain of a lab animal. In most cases, experimental ablation does not involve removal of brain tissues; instead, the researcher destroys some tissue and leaves it in place. It is the oldest method used in neuroscience. Lesion study: experimental ablation (purposely causing a wound)
