PHAR 100 Chapter Notes - Chapter 3: Obsessive–Compulsive Disorder, Generalized Anxiety Disorder, General Anaesthesia

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Inherent harmfulness: potential of the drug to cause harm. If a drug can cause serious health effects, it would not be used even if widely available. Low high (anti-anxiety sedation hypnosis general anesthesia) Anti-anxiety: used to treat anxiety disorders, such as generalized anxiety disorder and obsessive- compulsive disorder. Sedation: used to treat anxiety, decrease activity, moderate excitement, and generally calm the individual. Hypnosis (sleep): used to produce drowsiness and aid in the onset and maintenance of sleep. General anesthesia: used to induce general anesthesia, which is a state of unconsciousness with an absence of pain sensation. The major excitatory neurotransmitter in the brain is glutamate (from module 2). When in insomnia, therapies aim to depress overall brain activity or decrease glutamate-induced nerve firing. This can be accomplished by increasing inhibitory signalling in the brain. See diagram: most brain activity involves excitatory neurons.

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