BPK 140 Chapter Notes - Chapter 2: Natural Killer Cell, Lymphopoiesis, Adaptive Immune System

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Overview of the immune system - https://www. niaid. nih. gov/research/immune-system- overview. Function: prevent or limit infection, the immune system can distinguish between normal, healthy cells and unhealthy cells by recognizing a variety of danger" cues called danger-associated molecular patters (damps) Infectious microbes such as viruses and bacteria release another set of signals recognized by the immune system called pathogen-associated molecular patterns (pamps) If an immune response cannot be activated, infection can arise. If activated without a real threat, allergic reactions and autoimmune diseases arise. Immune cells come from precursors in bone marrow: develop into mature cells through a series of changes that can occur in different parts of the body, skin, first line of defense, produce and secrete important antimicrobial proteins. Immune cells constantly circulate throughout the bloodstream: patrols for problems. Features of an immune response - https://www. niaid. nih. gov/research/immune-response- features: divided into innate and adaptive immunity.

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