PSYD35H3 Chapter Notes - Chapter 3: Acetylcholinesterase, Psychoactive Drug, Metabotropic Receptor
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The body experiences effects that are characteristic for the drug: the pharmacological, physiological, or behavioural effects induced by a drug follow from their interactions with receptors. Pharmacokinetics: study of what the body does to a drug. Pharmacodynamics study of what the drug does to the body. A receptor is a fairly large molecule at which endogenous transmitters or modulators produce their biological effect. Drugs do not create any unique effects; they merely modulate normal neuronal functioning, mimicking, or antagonizing the actions of a specific neurotransmitter. Each of these subunits is made up of four helical coils, which also. The ultimate cellular response produced by this process may be the opening of ion channels, the alteration of enzyme activities, or changes in gene activation. One major advantage of the g-protein-coupled receptors is signal amplification: g-protein-coupled receptors are able to effect communication between the neurotransmitter-receptor complex and intracellular enzymes, the second messengers, to produce the ultimate biological response.
