PSYB65H3 Chapter 13: Neural Development and Developmental Disorders
Document Summary
Neural plate: neural plate formed from ectoderm on dorsal surface of embryo that becomes nervous system: pluripotent stem cells: have the potential to turn into different types of nervous system cells. Neural tube: day 24 fusing of neural plate; different sections become different parts of system, interior surface becomes ventricles and central canal of spinal cord. Proliferation: months 3-5; rapid division of cells of the neural tube within the ventricular zone. Day 40: three bumps on anterior portion of neural tube forebrain, midbrain and hindbrain. Inside part develops first then moves outward in waves of proliferation and migration guided by glia as well as growth of axons and dendrites. Month 2: telencephalon goes through lots of growth developing cortical plate. Adverse events: genetic or chromosomal abnormalities or intrauterine trauma or exposure to toxins. Craniorachischisis: neural tube fails to close, 1/1000 live births. Spina bifida: incomplete closing of posterior neural tube; locomotive problems.
