BIO130H1 Chapter : Pg. 695-707.docx

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BIO130H1 Full Course Notes
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All eukaryotic cells have the same basic set of membrane-enclosed organelles. Cytoplasm: consists of the cytosol and cytoplasmic organelle. Cytosol: site of protein synthesis and degradation; more than 50% Rough er: has ribosomes bound to it; synthesize protein. Lysosomes: contain digestive enzymes that degrade defunct organelles. Peroxisomes: has enzymes that can perform oxidization processes. Evolutionary origins explain the topological relationships of organelle. Organelles such as chloroplasts and mitochondrion are said to have been engulfed by the cell. Proteins can move between compartments in different ways. All proteins end up in the cytosol and require sorting. Proteins contain sorting sequences that determine where the protein should go. Gated transport: proteins that move between cytosol and nucleus; the proteins travel through nuclear pore complexes. Transmembrane transport: protein translocators can transport the proteins to the appropriate place. Vesicle transport: transfer proteins through vesicles; fragment compartments. Signal sequences direct proteins to the correct cell address.

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