KINE 1P90 Lecture 12: PEKN 1P90 Lecture 12: 1P90 lec 12:16

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All lectures are posted on sakai and tophat. Study to learn, not to pass midterm. Functions of cells (common functions that all cells have, special functions of cells) Feedback loops: negative vs positive feedback with examples. Decrease in calcium turns o sliding process. Thin laments on each side of sarcomere slide inward over stationary thick laments toward centre of a band during contraction. As thin laments slide inward, they pull z lines closer together. All sarcomeres throughout the muscle bre"s length shorten simultaneously. Contraction is accomplished by thin laments from opposite sides of each sarcomere sliding closer together. Activated cross bridge bends toward centre of thick lament, rowing in the thin. Myosin heads swivel toward centre of sarcomere (power stroke) Atp binds to myosin head and detaches it from actin. One motor mourn and the muscle bres it innervates. Number of muscle bres varies among di erent motor units.

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