PHGY 314 Lecture 3: Brandon - lecture 3
11 Feb 2017
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Anatomy and physiology of hdcs, place cells and grid cells (part ii) Overview: how are place cells generated, the discovery of grid cells and their characteristics, boundary vector cells and the boundary vector cell model, speed cells in the hippo, time cells in the hippo and entorhinal cortex. At first, researchers recorded downstream of ca1 in the ec to see if the spatial signal was coming from there. They saw very sparse, loose place fields (pfs) that did not look like great signals. So this is probably not the signal that is coming into the hippo to generate the hippo place cells. The conclusion was that somehow, somewhere in the ec, there is an input going directly to ca1 to give rise to the place cells. They revisited the ec and took several recordings to try to find something meaningful. The ec is separated into the lateral and medial entorhinal cortices. 2 regions have distinct projection patterns into the hippo.
