MBIO 2360 Lecture Notes - Lecture 21: Fructose-Bisphosphate Aldolase, Adenine, Adenylate Kinase

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Cells use compounds with a high free energy of hydrolysis to make atp: this is called substrate level phosphorylation. In glucose oxidation, there are 3 steps where atp is produced by directly coupling its formation to an energy releasing reaction. Two other processes for producing atp are: oxidation phosphorylation in mitochondria. Couples atp formation to energy release redox reactions: photophosphorylation in chloroplasts. Couples atp formation to energy derived from absorption of visible light. The free energy of hydrolysis of atp, -30. 5 kj/mol, is high enough to drive a large number of other reactions: this free energy change is greater than that accompany most other biological reactions. As a result, the gamma phosphate of atp is often called high energy phosphate. Atp cleavage sometimes occurs between the a and b phosphates: ppi = -45. 6 kj/mol. The following reactions release similar g as atp hydrolysis: adp + h2o -> amp + pi.

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