BIO 1140 Lecture Notes - Lecture 10: Nuclear Membrane, Phosphatidylserine, Intermediate Filament

38 views3 pages
Thu, February 11 - Lecture 10 Mitochondria part 2 (Cell death)
Slide 4
cells can grow, there needs to be a limit, and it is advantageous to be able to get rid of cells
Slide 5
there are cell cycle checkpoints where they check cells to make sure that they are healthy, being
useful. etc.
Slide 6
each nematode identical number of cells, making them easy to track (very unlike humans),
limited number of cells makes it easy to compare it to organisms with more cells
Slide 7
when they develop into adult nematodes, the same 131 cells apoptose every time
Slide 8
Necrosis: the cell swelled and membrane bursts (as soon as it swells it is inevitable that the cell
will die
Slide 8
Apoptosis: the cell shrinks and breaks into fragments,
Slide 9
Apoptosis is a very clean process and does not effect outside environment, whereas Necrosis is
when the membrane bursts, allowing all it's inner substances out into the environment, affecting
other cells
Slide 11
intercellular Ca concentration grows too high, convinces the endoplasmic reticulum to release all
of the Ca from storage. (remember all of this Ca is now toxic and released in the cytoplasm)
Slide 11
Caspian becomes activated when too much Ca in the cell, goes straight to the lysosomes and
disintegrate the membranes, which releases the powerful destructive enzymes they were storing.
They are then free to chomp on anything they can get to within the cell (cytoskeleton, organelles,
membranes, EVERYTHING) i.e. Cathespin (one of these very destructive enzymes released
from lysosomes rupturing)
Slide 12
In comparison, apoptosis is much more structured and organized. As it dies, it is structured and
packaged into smaller portions. Once the cell interprets a change in its environment that it must
undergo apoptosis, it condenses the chromatin and begins to shrink. The cytoplasm starts to
disintegrate, microtubules unravel, microfilaments shrink, everything inside becomes much less
organized and protected, but is easier to start breaking down. DNA fragments start breaking
down into smaller portions, everything in extracellular space also starts breaking down, cell
find more resources at oneclass.com
find more resources at oneclass.com
Unlock document

This preview shows page 1 of the document.
Unlock all 3 pages and 3 million more documents.

Already have an account? Log in

Document Summary

Thu, february 11 - lecture 10 mitochondria part 2 (cell death) Slide 4 cells can grow, there needs to be a limit, and it is advantageous to be able to get rid of cells. Slide 5 there are cell cycle checkpoints where they check cells to make sure that they are healthy, being useful. etc. Slide 6 each nematode identical number of cells, making them easy to track (very unlike humans), limited number of cells makes it easy to compare it to organisms with more cells. Slide 7 when they develop into adult nematodes, the same 131 cells apoptose every time. Necrosis: the cell swelled and membrane bursts (as soon as it swells it is inevitable that the cell will die. Apoptosis: the cell shrinks and breaks into fragments, Apoptosis is a very clean process and does not effect outside environment, whereas necrosis is when the membrane bursts, allowing all it"s inner substances out into the environment, affecting other cells.

Get access

Grade+
$10 USD/m
Billed $120 USD annually
Homework Help
Class Notes
Textbook Notes
40 Verified Answers
Study Guides
Booster Classes
Class+
$8 USD/m
Billed $96 USD annually
Homework Help
Class Notes
Textbook Notes
30 Verified Answers
Study Guides
Booster Classes