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Class Notes for Ian Orchard

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UTMBIO304H5Ian OrchardWinter

BIO304H5 Lecture Notes - Lecture 7: Sodium-Potassium Alloy, Tetrodotoxin, Repolarization

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15
Depolarization is not normally possible in cell at rest. Conductance is controlled by ion channels: if channels are closed it should be 0. Rising phase
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UTMBIO304H5Ian OrchardWinter

BIO304H5 Lecture Notes - Lecture 13: Membrane Potential, Voltage Clamp, Reversal Potential

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Curare: blocks acetocholine antagonist: no stimulation of the muscle. Vertebrate neuromuscular junction: have end plate potentials, junctional folds in
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UTMBIO304H5Ian OrchardWinter

BIO304H5 Lecture Notes - Lecture 9: Cardiac Muscle, Pacemaker Current, Depolarization

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15
No hyperpolarization because competing sodium current for. Transmit signals just in the form of graded potentials. Signals degrade over length: shorter
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UTMBIO304H5Ian OrchardWinter

BIO304H5 Lecture Notes - Lecture 4: Goldman Equation, Nernst Equation, Extracellular Fluid

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13
Relative number of ions inside the cell is small: doesn"t take many ions for resting membrane potential to develop. To make inside slightly negative co
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UTMBIO304H5Ian OrchardWinter

BIO304H5 Lecture Notes - Lecture 5: Action Potential, Squid Giant Axon, Membrane Potential

OC2208001 Page
17
Greater number of k+ leaky channels in membrane: k+ makes a greater contribution. Cl is limited by fewer leaky channels. Squid giant axon is permeable
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