HMB265H1 Lecture Notes - Lecture 9: Bipolar Disorder, Chromosome, Dominance (Genetics)

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burgundymule401

31 Jan 2018

School

UTSG

Department

Human Biology

Course

HMB265H1

Professor

Maria Papaconstantinou

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HMB265H1 Full Course Notes

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Genotype frequenciesn in a population are determined by the processes of an individual. To be able to relate this individual genetic processes to genetic populations, we have to study different factors that affect allele frequencies. one gene flow can be migration, its where alleles move between populations and mate. Another factor is mating patterns, another is mutations. Natural selection where different genotypes have different chances of survival. A phenotype frequency is the proportion of individuas in a population that express a particular phenotype and these differ for different populations. They both siscovered independently that random mating results in an equilibrium frequency of ge(cid:374)otypes, that (cid:396)a(cid:374)do(cid:373) (cid:373)ati(cid:374)g does(cid:374) t cha(cid:374)ge ge(cid:374)otype f(cid:396)e(cid:395)ue(cid:374)cies. This maintains genetic differentiation within a generation and from one generation to the next. There has to be no genetic drift that occurs. We know that all of these assumptions are most likely violated in real populations.

Related Questions

44.Why donât similar genotypes always produce the same phenotype?

A. Parent alter their phenotype and pass on this phenotype to progeny

B. Phenotype is the product of many environmental influences

C. Genetic variations of ADH enzyme produce the same phenotype

D. Animals display different phenotypes dependent on diet, not genotype

46.Which of the following attributes has the least effect on the contribution an individual makes to the gene pool of the next generation?

A. spas of mating privileges

B. more efficient at obtaining food

C. produces more offspring

D. camouflage from predators

47.âUntil the agricultural evolution 10,000 years ago, people used to live in small populations with little gene flow between them. That is the best situation for rapid evolution.â said Sewall Wright. one of the founders of population genetics. This conclusion on gene flow conflicts with Hardy Weinberg equilibrium, which states that no gene flow means

A. natural selection

B. no evolution

C. no random mating

D. no genetic drift

58 Larval flies (maggots) express the Ubx gene in all of their segments, and thereby lack appendages. If this same gene continued to be expressed throughout subsequent developmental stages, except in the head region, and if the result was a fit, sexually mature organism that still strongly resembled a maggot, this would be an example of

A. homochrony

B. exaptation

C. paedomorphosis.

D. adaptive radiation

raspberrymole848

Need help with evolution questions:

1.) A haplotype is best defined as the ________________.

	haploid genotypes of all the gametes produced by a diploid individual

ABO blood type conferred by an individual gamete

genotype of either the paternal or maternal chromosomal complement

multilocus genotype of a chromosome or gamete

2.) Which of the following statements regarding linkage disequilibrium is true?

Exists when D is less than zero, but not when it is greater than zero.

Is reduced by sexual reproduction.

Is increased by crossing-over during meiosis.

Is increased by any random sampling error that happens to create or destroy certain chromosome genotypes but not others.

Is reduced by selection that favors certain combinations of genotypes.

3.) Selection on multilocus genotypes in random-mating populations leads to linkage disequilibrium when _______________.

it reduces mutation rates

it eliminates all haplotypes from the population

it prevents crossing-over during meiosis

some allele combinations confer greater fitness than do others

4.) When two loci are in linkage equilibrium, the allele carried on a chromosome at one locus is independent of the allele carried on the chromosome at another locus. When this is the case, _________________.

allele frequencies will not change over time

the two loci (or, more specifically, their protein products) do not interact

the frequency of each haplotype can be calculated by multiplying the frequency of its two alleles

all possible haplotypes occur at equal frequency

5.) Which of the following accurately characterize(s) Muller's ratchet model for the selective advantage of sexual reproduction?

Drift establishes linkage disequilibrium because multilocus genotypes with few mutations are eliminated by chance events.

In populations without sexual reproduction, deleterious mutations accumulate, eventually imposing such a burden that the population goes extinct.

Sex is favored selectively because it recreates the zero-mutation genotypes lost due to drift.

All of the above correctly characterize Muller's ratchet model for the evolution of sexual reproduction.

6.) The genetic signature of recent positive selection on a locus is _______________.

high frequency and low linkage disequilibrium

low frequency and low linkage disequilibrium

low frequency and high linkage disequilibrium

high frequency and high linkage disequilibrium

7.) Sexual reproduction is advantageous both in changing environments and in constant environments, compared to asexual reproduction.

True

False

8.) Sexual reproduction causes genetic recombination via crossing-over, which combines genotypes from different parents.

True

False

9.) One reason sex may be maintained in natural populations is proposed by the "Red Queen Hypothesis", which states that.....

genotypes created by sex are created by natural selection over and over

recombination creating novel genotypes that can resist infection by parasites

mutation load is reduced by novel adaptive mutations

the ability of sex to fix multiple

1) Which of these probabilities are NOT independent of eachother?

The probability that a student is a sophomore and has brownhair

The probability that when you roll two dice, you will roll a 6before a 2

The probability that it will rain and the probability ofneeding an umbrella

The probability that there will be heavy traffic on BaltimoreAve and the probability you will lose your cell phone

2) We are defining evolution as a "change in allele frequenciesover time". Ironically, the focus of this lab is the Hardy-Weinbergequilibrium - conditions that, if all met, will result in NOevolution occurring. Which of the following are among theconditions that must be met for the Hardy-Weinberg equilibrium toapply perfectly to a population?

A. The population must be very large

B. Individuals must mate at random

C. The alleles must differ in their effects on survival

D. There must be free migration into and out of thepopulation

A & B

A, B, & C

3)In cats, black fur is dominant over any allele for brown fur.If a homozygous dominant cat makes kittens with a heterozygous cat,what is the probability that the first kitten will have brown fur?Report as a proportion, not percentage, e.g., .1, NOT 10%.

The EGLN1 gene helps regulate body oxygen levels. One allele His dominant over h, and helps increase fitness at high altitude(where oxygen is low). In a study of families in Tibet, researchersfound 422 HH individuals, 377 Hh, and 201 hh individuals. The studyshowed that infant mortality was lower in Hh individuals than hh,and lowest in HH individuals.
Is the Tibetan population in Hardy Weinberg Equilibrium at this H/hgene?

What is the most important factor affecting the strength ofgenetic drift?

The frequency of the rarest genotype

The size of the population

The allele frequencies

The genetic diversity in the population

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HMB265H1 Lecture Notes - Lecture 9: Bipolar Disorder, Chromosome, Dominance (Genetics)

HMB265H1 Full Course Notes

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