IMM250H1 Lecture Notes - Luxol Fast Blue Stain, Cerebrospinal Fluid, Gadolinium
Document Summary
B cells regulatory one to five percent in system expand when in contact with with. Cd19 no b10 cells used as negative control. Monensin to stain for intracellular cytokine production. Cells increased three fold il10 in supernatant increased by five fold. Aberrant immune response from body attack proteins expressed result in pathology can be fatal. Pro-inflammatory environment higher rate of diabetes type two, heart disease, etc. Striking sex difference not all autoimmune diseases systemic females around nine or ten times more than males strong female bias . Classification organ specific or systemic (full blown; multiple organs affected) Trained to recognize certain antigen and that"s where the attack is oriented. Type of immune effector mechanism in place type of immune cells making attack on organ or myelin sheath immune effector mechanism applicable broadly to immune responses in general. Classical allergy mast cells histamine release inflammation in skin no type one autoimmune diseases.
