1 A 5-year old girl displayed increased appetite, increasedurinary frequency, and thirst. Her physician suspected new onsetdiabetes mellitus and confirmed that she had elevated urine glucoseand ketones. Blood glucose levels were 250mg/dL (normal range 90-120 mg/dL).
In the girl presenting above, the increase in blood glucose isprimarily due to which of the following?
Increase heptic gluconeogenesis
Increase lipolysis
Decrease in glucose uptake by GLUT 2
2 Under fed conditions, all of the following are true statementsexcept:
Citrate is shuttled out of the mitochondria
The pyruvate dc is activated by pyruvate
The phosphatase activity of PFK2 26 bisphasphate is active
Pyruvate kinase is allosterically activated by F 1 6phosphate
3 Somatostatin and glucagon both signal through G-proteincoupled receptors but they elicit different responsesbecause:
Somostatin uses Ca2 as a downstream signal glucagon uses camp asdownstream
Somatostatin activates an inhibitory G protein glucagon activatesan activator G proton
Somostastarin activates MAPK cascade glucagon activates anactivator G protein
Somatostatin activates an activator G protein glucagon activates aninhibitory G protein
1 A 5-year old girl displayed increased appetite, increasedurinary frequency, and thirst. Her physician suspected new onsetdiabetes mellitus and confirmed that she had elevated urine glucoseand ketones. Blood glucose levels were 250mg/dL (normal range 90-120 mg/dL).
In the girl presenting above, the increase in blood glucose isprimarily due to which of the following?
Increase heptic gluconeogenesis
Increase lipolysis
Decrease in glucose uptake by GLUT 2
2 Under fed conditions, all of the following are true statementsexcept:
Citrate is shuttled out of the mitochondria
The pyruvate dc is activated by pyruvate
The phosphatase activity of PFK2 26 bisphasphate is active
Pyruvate kinase is allosterically activated by F 1 6phosphate
3 Somatostatin and glucagon both signal through G-proteincoupled receptors but they elicit different responsesbecause:
Somostatin uses Ca2 as a downstream signal glucagon uses camp asdownstream
Somatostatin activates an inhibitory G protein glucagon activatesan activator G proton
Somostastarin activates MAPK cascade glucagon activates anactivator G protein
Somatostatin activates an activator G protein glucagon activates aninhibitory G protein
