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22 Feb 2018

Why is the citric acid cycle central to biosynthetic pathways, as well as to catabolism?

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Beverley Smith
Beverley SmithLv2
25 Feb 2018
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Related questions

Discuss connectivity between the following metabolic pathways:

Heme Biosynthesis and The Citric Acid Cycle

Fatty Acid Catabolism and The Citric Acid Cycle

How does catabolism of glucose from dietary carbohydrates link to fatty acid synthesis?

Choose one or more:

A. Catabolism of excess dietary carbohydrates raises the energy charge of the cell, which slows the flux of the citric acid cycle.

B. Glycolytic intermediates can be used as substrates for fatty acid and triacylglycerol synthesis.

C. Increased flux of the citric acid cycle produces NADH, which can be used for fatty acid synthesis.

D. Catabolism of excess dietary carbohydrates reduces fatty acid oxidation.

The citric acid cycle is described as the major pathway of aerobic catabolism, which is an oxygen- dependent degradative process. However, none of the reactions of the cycle directly involves oxygen as a reactant. Why is the pathway oxygen-dependent?

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