🏷️ LIMITED TIME OFFER: GET 20% OFF GRADE+ YEARLY SUBSCRIPTION →
Log in
Biology
1
answer
0
watching
176
views
1 Nov 2018

22. What is one possible reason why nonstandard base pairing (wobble) is allowed during protein synthesis?

Note; please state the sources for the answers

Watch
1
answer
0
watching
176
views

For unlimited access to Homework Help, a Homework+ subscription is required.

Nelly Stracke
Nelly StrackeLv2
4 Nov 2018

Unlock all answers

Get 1 free homework help answer.
Already have an account? Log in
Share

Related textbook solutions

Molecular Cell Biology
8 Edition,
Lodish
ISBN: 9781464183393
Biology: Science for Life with Physiology
6 Edition,
Belk
ISBN: 9780134555430
Concepts of Biology
OER Edition,
Openstax
ISBN: 9781938168116
Biology
2nd Edition, 2013
Openstax
ISBN: 9781947172517
Essentials of Biology
5 Edition,
Mader
ISBN: 9781259660269

Related questions

A single base substitution in the anticodon loop of one of thetRNAs for glutamic acid (tRNAglu) can hypothetically generate amutant tRNA that is able to suppress translational termination bycausing insertion of a glutamic acid residue at certain terminationcodons. Such mutant tRNAs are in fact encountered in nature and arereferred to as suppressor tRNAs. Assume that there are two tRNAgenes for glutamic acid (so that this hypothetical mutation wouldnot be lethal) and that one of these tRNAs acquires a single basemutation in its anticodon loop. Assume also that this tRNA has a Uresidue at the wobble position (and can therefore base pair withboth Glu codons) and that the mutation does NOT occur at thiswobble position.

A) What is the nucleotide sequence of the wildtype anticodon oftRNAglu (5’?3’ polarity) and what is the mutant sequence that wouldhave the properties described above?

Wt sequence:

Mutant sequence:

B) At which stop codons would the mutant tRNAglu be able tosuppress translational termination? (assume that G-U base pairingis possible at the wobble position)


C) Mutations of the sort described above are rarely encountered innature, due in part to the existence of a key step in the chain ofevents that helps ensure translational fidelity. What is this stepand how might it prevent suppressor tRNAs from being able toincorporate amino acids at stop codons?

Trying to work out and reason through this practice question tohelp me on my test.

"Briefly explain why non-homologous end joining is overwhelmingfavored over homologous recombination repair for fixing doublestrand DNA breaks in mammalian cells in G1. Why is this biasreversed during G2?"

So I reckon that non-homologous end joining is favored in G1because although original base pairing is lost and chewed back byexonuclease before the DNA is re-ligated, the loss of base pairsisn't critical due to the imminent S phase, which will ensure theDNA is further re-synthesized, thus mitigating the effect of lostbase pairs.
However, for G2, nonhomologous recomb. is favored because in thismethod base pairs are re-added before getting re-ligated, ensuringno bases are lost. This is critical because the next phase ismitosis, and all of the DNA must be synthesized to this point; anyloss of DNA before mitosis would probably lead to mutations whenthe cell eventually divides.

Is my reasoning accurate? Please chime in anddiscuss!

PLEASE ANSWER ALL THE QUESTIONES BELOW AS DETAILED AS POSSIBLE. THANK YOU!

Why do all (-)RNA virus have an RNA polymerase in its virion?

How does vesicular stomatitis virus regulate its mRNA transcription?

How does vesicular stomatitis virus regulate Protein synthesis?

State numerous factors for Ebola virus being an emerging deadly pathogen for us.

Why can’t influenza virus replicate in a cell where the nucleus has been removed?

PLEASE ANSWER ALL THE QUESTIONES ABOVE AS DETAILED AS POSSIBLE. THANK YOU!

Related Documents

BIO206H5 Lecture Notes - Lecture 14: Aminoacyl-Trna, Wobble Base Pair, Aminoacylation
crimsonsnake651
BIO 2133 Chapter Notes - Chapter 13: Precursor Mrna, Five-Prime Cap, Chromatin
blushcaribou532
BIO 2306 Chapter Notes - Chapter 15: Stop Codon, Carboxylic Acid, Reading Frame
sangriaskunk365

Weekly leaderboard

Home
Homework Help 3,900,000
Biology 460,000
Start filling in the gaps now
Log in