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2 Jan 2018

A person has been bitten by three mosquitoes over the past month and infected each time with malaria. The first time, the person was infected with drug-sensitive wild-type malaria. The second time the person was bitten with chloroquine-resistant malaria, and the third time with artemisinin-resistant malaria. Each infectious bite gave rise to a clonal population of malaria parasites. The population size of the drug-sensitive parasites is 10^9. The population of the chloroquine-resistant parasites is 10^7. The population of the artemisinin-resistant parasites is 10^7. What is the heterozygosity of the malaria parasites circulating within this individual host?

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26 Aug 2021
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