answer

watching

views

17 Aug 2019

18) Explain why changes in oncogenes result in more rapid progression of a cancer compared to changes in tumor-suppressor genes (Hint: it is related to their mode of inheritance, i.e. dominant or recessive).

answer

watching

221

views

For unlimited access to Homework Help, a Homework+ subscription is required.

You have 0 free answers left.
Get unlimited access to 3.8 million step-by-step answers.

Get unlimited access

Already have an account? Log in

Patrina SchowalterLv2

18 Aug 2019

Unlock all answers

Get 1 free homework help answer.

Already have an account? Log in

Related questions

Explain in details. When oncogenes are activated by mutation we most often find that the mutation is a substitution, while when tumor suppressor genes are mutated the common mutation is an insertion/deletion. Why is this? p53 is a tumor suppressor gene yet mutations in p53 found in cancers are more often substitutions not insertion/deletions and these mutations are dominant, loss-of-function, as opposed to recessive. We call this type of mutation âdominant negativeâ â explain what is meant by that terminology. Explain how the inactivation of p53 is different than for other tumor suppressors.

greendeer380

Indicate whether each of the following descriptions better applies to proto-oncogenes (P) or tumor suppressor genes (T). Your answer would be a five-letter string composed of letters P and T only, e.g. PPPTT.

Cancer mutations in these genes are responsible for most hereditary cancers.

Cancer can result from translocations that place these genes under the control of wildly active promoters.

Cancer mutations in these genes are usually recessive.

These genes show increased promoter methylation in cancer cells.

Cancer mutations in these genes include gene duplications.

During the winter of your third year of medical school, you had the chance to work in a cancer lab, to analyze gene from patients. You were given data through microarray so you can compare cancer with the normal tissues. ( hint: oncogenes, tumor suppressor genes) -> discovery of your own.

1. What experiment would you do to test the suppressor gene or potential oncogene

3. What technique will you apply if you think chromosomal translocation are the cause of abnormal gene activity.

Weekly leaderboard

Home

Homework Help 3,900,000

Biology 460,000

18) Explain why changes in oncogenes result in more rapid progression of a cancer compared to changes in tumor-suppressor genes (Hint: it is related to their mode of inheritance, i.e. dominant or recessive).

Unlock all answers

Related textbook solutions

Molecular Cell Biology

Biology: Science for Life with Physiology

Concepts of Biology

Biology

Essentials of Biology

Related questions

Related Documents

BIO230H1 Lecture Notes - Lecture 12: Mutagen, Myc, Mansio

BIO230H1 Lecture Notes - Lecture 24: Tumor Suppressor Gene, Cytochrome P450, Aflatoxin

BIOS 222 Lecture Notes - Lecture 19: Tumor Suppressor Gene, Cell Cycle Checkpoint, Anaplasia

Weekly leaderboard