🏷️ LIMITED TIME OFFER: GET 20% OFF GRADE+ YEARLY SUBSCRIPTION →
Log in
Biology
4
answers
0
watching
27
views
18 Dec 2019

5'...caugauaaGUagcgcu....guuccAccguu.....uucugcAGauuucaugau...3'

make a simple line diagram of the lariat structure of thediscarded intron for most of the RNA sampling strand and showingthe location of all 5 nucleotides that are in bold typeface above.label and loose ends of the structure 3' or 5'

Watch
4
answers
0
watching
27
views

For unlimited access to Homework Help, a Homework+ subscription is required.

Unlock all answers

Get 1 free homework help answer.
Get unlimited access
Already have an account? Log in
Share
Get unlimited access
Already have an account? Log in
Share
Get unlimited access
Already have an account? Log in
Share
Get unlimited access
Already have an account? Log in
Share

Related textbook solutions

Molecular Cell Biology
8 Edition,
Lodish
ISBN: 9781464183393
Biology: Science for Life with Physiology
6 Edition,
Belk
ISBN: 9780134555430
Concepts of Biology
OER Edition,
Openstax
ISBN: 9781938168116
Biology
2nd Edition, 2013
Openstax
ISBN: 9781947172517
Essentials of Biology
5 Edition,
Mader
ISBN: 9781259660269

Related questions

30. Which TWO modifications of heterogenous nuclear RNA is important for the stability of the transcription and for its translation?

31. Below is a sequence of a heterogenous nuclear RNA with exons shaded grey and nucleotides that are important for splicing indicated in bold.

...cacccggctcccgcttcacctggggcacagtgcaggtggtcacaggccaagcgggcacgcccactgtgccccccgaccccagcccacagg

ctcctgtccctgcccactcagcttcaaggcct…

Which cis-acting elements come into close proximity to form the lariat during splicing?

Extra credit: What is the protein that is translated from the mRNA indicated in questions 25 and 26 and what is its general function (hint: you will need to use one of the algorithms found on the NCBI website)?

Please help

1. Imagine you have been given the task of designing aninterfering RNA that is intended to reduce the level of proteinproduction from Gene A. Gene A’s genomic structure is shownbelow:

promoter = nucleotides 1-100

exon 1 = nucleotides 101-200

intron 1 = nucleotides 201-300

exon 2 = nucleotides 301-400

intron 2 = nucleotides 401-500

exon 3 = nucleotides 501-600

Imagine you have designed three interfering RNAs:

1. iRNA1 has a sequence that is identical to nucleotides 175-225in Gene A’s sequence (except there are Us in the RNA sequence wherethere are Ts in the DNA sequence)

2. iRNA2 has a sequence that is identical to nucleotides 325-375in Gene A’s sequence (except there are Us in the RNA sequence wherethere are Ts in the DNA sequence)

3. iRNA3 has a sequence that is identical to nucleotides 175-200in Gene A’s sequence joined with nucleotides 301-325 (except thereare Us in the RNA sequence where there are Ts in the DNAsequence)

Question: You already know that interfering RNAs can workthrough several different mechanisms. Imagine that both iRNAs areproperly designed, and both will bind to complementary sequences inboth DNA and RNA if they find any. Please describe thesimilarities and differences in the mechanisms you expect theseiRNAs to be able to work through. Include mention of whether youthink each iRNA will work at low concentration (3-4 molecules percell) as well as high concentration (3,000-4,000 molecules percell).

Biochem:

The following DNA template strand will be used for questions1-3: 3'- ATATCATCAGCA-5'

1. Reverse transcriptase is able to make DNA from RNA. Given theDNA segment from above, what would be the corresponding RNAsequence?

2. Suppose a problem with synthesis of nucleotides occurs thatcauses deoxygination of the 3' oxygen of deoxyribose of allcytosine bases, and only cytosine bases. What would be thesequences of the replicated strands of DNA?

3. Provide a method for how the scenario in question 2 could beused to create a method of sequencing. What molecular technique isthis similar to? What would the gel look like for the templatestrand?

4. Suppose that a deamination of a pyrimidine that iscomplementary to Guanine occurs in a strand of DNA. Explain theresulting problem and the process that is used to fix it.

5. Explain the properties of histones that allows for DNA to bepacked so closely together. BE sure to include the role that aminoacids play in this.

6. Suppose the sequence GGAUC is repeated infinitely. How manyamino acids would you find? List the amino acids you would find inthis motif.

7. Which of the following was improperly matched with a possibleanticodon?

a. M-AUG

b. Y-AUA

c. W-ACC

d. N-UUC

e. Q-GAG

f. A and C

g. A,D, and E

8. What is a lariat intron intermediate and explain the processused to temporarily create it?

Weekly leaderboard

Home
Homework Help 3,900,000
Biology 460,000
Start filling in the gaps now
Log in