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Midterm

test1-2012.pdf

5 Pages
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Department
Economics
Course Code
ECON 1540
Professor
Eytan Lasry

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Description
Name:_____ANSWERS______________________ Student number:_____ ANSWERS _______ FACULTY OF SCIENCE & ENGINEERING SC/BIOL 3155 3.0 - VIROLOGY MIDTERM TEST #1 (W12) Feb. 9, 201288 INSTRUCTIONS: (1) Fill in your NAME and STUDENT # on ALL 5 pages of this Test booklet & the Scantron Sheet. (2) Multiple choice questions have only ONE (1) CORRECT answer. Fill in answer on the Scantron Sheetupplied – only the scantron sheet will be marked. (3) The test is divided into 3 Sections. Section I Multiple choice 10 marks (1 mark per question) Section II Written answers 15 marks Total marks: 25 Section III Bonus question 1 marks (4) Answer ALL questions. (5) NO calculators are permitted. (6) Total time: 80 mins (7) Hand in your Entire Test Booklet and Scantron Sheet - missing page(s) will receive zero. GOOD LUCK! 1 Name:_____ANSWERS______________________ Student number:_____ ANSWERS _______ SECTION I: Answer ALL questions 1 - 10 in this section on the SCANTRON SHEET (1) Which of the following statements is correct? A. viral envelope proteins are never glycosylated B. viruses do not have phenotypes C. one of the discoverers of interferon was Weller D. like some viruses, some small bacteria use RNA to store their genetic information E. a filterable agent passes through the filter F. the ratio of (physical : infectious) particles can be (1 : >1), respectively G. none of the statements above is correct (2) Which of the following is a correct match? (the two halves of each match are separated by " ") A. 1 HAU  ≥100000 virus particles B. hemorrhagic fever  Rhinovirus C. discovery of cellular oncogenes  Temin & Baltimore D. fission  virus E. tropism  eclipse F. cRdDp  ssDNA virus G. none of the above is a correct match (3) How many 6-fold axes are there in a T=7 particle? A. 20 B. 30 C. 50 D. 60 E. 70 F. 90 G. none of the answers above is correct (4) The following degrees: 180°, 72° and 120°, correspond to the following rotational symmetries? A. 2-fold, 3-fold and 5-fold B. 2-fold, 5-fold and 3-fold C. 3-fold, 2-fold and 5-fold D. 3-fold, 5-fold and 2-fold E. 5-fold, 3-fold and 2-fold F. 5-fold, 2-fold and 3-fold G. none of the answers above is correct (5) Plant viruses are generally named based on which of the following? A. location B. a number C. a letter D. host E. disease name F. particle shape G. two of the answers above are correct 2 Name:_____ANSWERS______________________ Student number:_____ ANSWERS _______ (6) Which of the following is not a correct match? A. ssDNA virus  Circoviridae B. dsDNA viruses  segmented genomes C. (+)strand RNA viruses  all lineagenomes D. (-)strand RNA viruses  all helicacapsids E. dsRNA viruses  all icosahedral capsids F. reverse transcriptase  Caulimoviridae G. viroids  infect plants only H. none of the above is the right answer to the question (7) Which of the following statements about poliovirus entry is not correct? A. Pvr is the receptor on epithelial cells B. the canyon is in VP1 C. there are twelve different positions in the particle that could form a pore D. the pore forms at the 6-fold axis E. pore formation involves externalization of VP4 F. pore formation occurs at the endosomal membrane G. none of the above is the right answer to the question (8) Which of the following statements about Influenza virus entry is correct? A. HA is a tetramer B. fusion occurs at the cell membrane C. fusion is pH-independent D. NA is a type-I protein E. hemifusion occurs after fusion F. M2 is part of the nucleocapsid G. NA facilitates virus exit H. none the answers above is correct (9) What experiment demonstrated that translation of the lysis protein did not require disruption of the lysis RNA hairpin? A. introducing a stop codon before the lysis start codon B. introducing a second start codon after the lysis start codon C. changing the two stop codons for the CP ORF to start codons D. introducing a stop codon before the MJ double stranded structure E. introducing a stop codon after the MJ double stranded structure F. destabilizing the operator hairpin G. none the answers above is correct (10) Which polymerase is used by lambda during virus replication? A. vDdDp B. cRdDp C. cDdRp D. vDdRp E. cRdRp F. vRdDp G. none the answers above is correct 3 Name:_____ANSWERS______________________ Student number:_____ ANSWERS _______ SECTION II: Answer ALL QUESTIONS in this section ONLY in the spaces provided. [1] You plate 1 ml of a diluted phage preparation that was given to you and incubate the Petri dish overnight. The next day you count 4 larg
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