PHAR 100 Lecture Notes - Lecture 25: High-Protein Diet, Anabolic Steroid, Blood Doping

• School: Queen's University
• Department: Pharmacology and Toxicology
• Course: PHAR 100
• Professor: Bill Racz

Document Summary

*reduce pain and inflammation local anesthetics, narcotics and corticosteroids. *increase endurance and speed amphetamines and blood agents. *masking taking a naturally occurring compound which is excreted with the drug. Excreted independently thus smaller amounts can be taken not detected. *pyramiding building up the dose and then tapering off so that drug free by competition date. Doping control often though measuring drug in urine or through endogenous factors ie. change in normal hormone levels with anabolic steroid use synthesized testosterone is an isotope of regular testosterone. Toxicities: increase heart rate and blood pressure which can be fatal and create cns excitation. Modofinil produced an amphetamine like response without the jitteriness. Require a high protein diet because you need amino acids to build muscle. Produce secondary sex characteristics . ie) stanozolol used for disease states for muscle wasting states. Conflicting evidence for efficacy suggests as do not work but elite athletes are using them as 20 200 times the therapeutic dose!