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Lecture 32

BIOA01H3 Lecture 32: Module 3 Lecture 32.docx

Biological Sciences
Course Code
Effiette Sauer

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Module 3
Lecture 32: Central Dogma
Outline for Lecture 32
Connection between DNA, RNA and Protein
One – gene - one polypeptide
Beadle and Tatums Experiments
- Grew nuitrional mutants (autotrophs) of neospora on a minimal medium
supplemented with single amino acids (arginine)
oHypothesis: Each auxotrophic strain had a defect in a gene that codes for
an enzyme needed to synthesize particular amino acid
Results: Blockage at each step of enzyme pathway, each gene encodes only 1 polypeptide
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