BIO120H1 Lecture : Notes taken during lecture
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BIO120H1 Full Course Notes
Verified Note
36 documents
Document Summary
Depending on cell can have one golgi or more if cell involved in secretion, can have 100. er sends transport vesicles to er, fuse together, form cis golgi structure. sorting mechanism that occurs in transgolgi network. Chaperone proteins responsible for holding misfolded or unfolded protein in er. copii-coated vesicles: vesicular tubular cluster attached by motor proteins to microtubule migrate towards golgi, shed copii coat , snares involved in vesicle fusion, transport vesicles, vesicular tubular cluster becomes the cis golgi network. Retrograde transport recovering the proteins that should be in er, but somehow left. proteins involved in vesicle budding from er : v-snares, rab-gtpases, etc. soluble with kdel signal: signal that brings it back into er if it escapes, bound by kdel receptor , four amino acids. kkxx pointing to the y receptor attached to blue labelled copi coat: signal bound by copi coats .
