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Department
Biology
Course
BIO120H1
Professor
Jean Jiang Nash
Semester
Winter

Description
LECTURE 8 Feb.1.2011 Sorting and packaging Depending on cell can have one Golgi or more if cell involved in secretion, can have 100 Golgi apparatus ER sends transport vesicles to ER, fuse together, form cis Golgi structure Sorting mechanism that occurs in transGolgi network Bud from ER exit sites Bound by cargo receptors Resident ER protein stays in ER Chaperone proteins responsible for holding misfolded or unfolded protein in ER Know specific names of these chaperones Cargo from ER to cisGolgi network COPII-coated vesicles o Vesicular tubular cluster attached by motor proteins to microtubule migrate towards Golgi o Shed COPII coat o SNAREs involved in vesicle fusion o Transport vesicles o Vesicular tubular cluster becomes the cis Golgi network
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