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8 Jan 2018

The change in cell morphology during the formation of somite segments from presomitic mesoderm is called __________________.

A.gastrulation

B. epithelial to mesenchymal transition

C. primitive streak regression

D. mesenchymal to epithelial transition

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10 Jan 2018
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Related questions

Address the following questions about the important developmental process called the Epithelial to Mesenchymal Transition (EMT).

(A) (5 points) Describe EMT and its relevance to developmental biology/embryogenesis.

(B) (6 points) What cell or tissue type would be most affected by inappropriate activation of EMT in adulthood, and what would be the result of reactivation of EMT in a differentiated cell or tissue of this type?

(C) (10 points) For the cell/tissue type in your answer from part (B), what specific behaviors/functions must be altered before cells in that tissue can become cancerous and metastatic?

(D) (4 points) Describe one tumor suppressor and one proto-oncogene whose expression would be altered upon EMT (specific gene names are not required, but you must indicate the class of protein that would be encoded by the genes you mention).

These are few questions I just want to confirm and few I am thoroughly confused with.

Q.1) What factor is expressed by the tail end of the presomitic mesoderm?

Answer: Is it fibloblast growth factors(fgfs)??

Q.2) What makes the pathways involved in the somite formation oscillate?

Q.3) How are genes silenced in RNA interference?What type of C.elegan genes are one of those affected?

Q.4) What intra-cellular filament is involved in bending ectoderm to form neural tube?

Answer: Is it actin filament?

Q.5) What defines the migration routes for the myoblasts?

Q.6) What signal does the notochord send? What determines the fate of the cells of the neural tube?

Thank you so much :D

1) Describe how do cell shape and changes in cell adhesiveness collaborate in the formation of the neural tube?

2) Somite formation in chick embryos proceed from anterior to posterior in reponse to a gradient of FGF8 gene expression. Describe this gradient:

a) Where does FGF8 originate?

b)Why does it form a gradient

c)How does the gradient trigger somite formation?

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