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PHAR 100 (42)
Bill Racz (11)
Midterm

PHAR 100 Midterm: Midterm Sample Questions

6 Pages
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Department
Pharmacology and Toxicology
Course Code
PHAR 100
Professor
Bill Racz

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PHAR 100 Midterm – Juy 2 Which one of the following statements best describes the concept of a placebo? Select one: a. A tablet that contains a full dose of the active ingredient being tested. b. A tablet that contains an inactive ingredient but looks like the tablet under test. c. A tablet containing a small amount of the active ingredient used as a control. d. A tablet that contains an active ingredient but looks like the tablet under test. e. A tablet containing a second drug similar to the one being tested but of known efficacy. Which one of the following statements regarding selective toxicity is correct? Select one: a. Pasteur and Koch demonstrated that certain diseases were caused by viruses. b. Sulfanilamide replaces folic acid in bacteria. c. Paul Erlich is credited with discovering the microscope. d. The first drugs considered to be selectively toxic were organo-arsenicals. e. Penicillin inhibits cell membrane formation. A person who has experienced severe respiratory depression due to an overdose with a psychoactive drug was successfully treated with naloxone. Which one of the following is most likely the offending psychoactive drug? (???????) Select one: a. Heroin. b. Cocaine. c. Secobarbital. d. Methadone. e. Amphetamine. The main clinical use of the barbiturates (phenobarbital) is to treat: Select one: a. Depression. b. Attention Deficit disorder. c. Insomnia. d. Epilepsy. e. Pyschotic episodes. Which one of the following statements is correct? Select one: (??????) a. Cocaine prevents the re-uptake of norepinephrine into adrenergic nerves. b. Ephedrine is approved for use in Canada for appetite control. c. Methylphenidate (Ritalin) is widely used in the treatment of depression. d. Methamphetamine releases transmitters from the parasympathetic nerve ending. e. Caffeine inhibits the uptake of serotonin into the neuron. The autonomic nervous system has as its major function: Select one: a. Control of emotion. b. Control of skeletal muscle and movement. c. Control of memory and cognition. d. Control of hormone dependent events. e. Control of the vegetative functions. Which one of the following drugs induces the greatest degree of reinforcement? Select one: a. Nicotine. b. Codeine. c. Heroin d. Cannabis. e. Morphine. Which one of the following statements is correct? Select one: a. Cannabis produces tolerance, addiction and physical dependence. b. Hallucinogens produce tolerance, physical dependence and addiction. c. Ethanol produces tolerance and addiction but not physical dependence. d. Opiates produce tolerance, but not physical dependence or addiction. e. Amphetamines produce physical dependence, addiction, but not tolerance. Which one of the following statements regarding the response to ethanol is correct? Select one: a. High doses of ethanol can cause a relaxed state through disinhibition. b. Consumption of ethanol does not follow a dose response relationship as most individuals react differently to ethanol. c. Acute high doses of ethanol can lead to black outs. d. Moderate doses of ethanol can improve male sexual performance. e. Small doses of ethanol (one drink) does not impair motor function. Which one of the following transmitters is correctly matched with its receptor. Select one: a. Norepinephrine – opioid b. Serotonin – Beta-2 c. Acetylcholine - Nicotinic d. Epinephrine – Muscarinic e. Dopamine – Beta-1 The organ which is the major route of elimination of many drugs that are excreted in an unchanged form is the: Select one: a. Liver b. Adrenal gland c. Kidney d. Lung e. Intestine Which one of the following mechanisms lead to the therapeutic action of chlorpromazine in patients suffering from schizophrenia? Select one: a. Blockade of dopamine receptors. b. Blockade of acetylcholine receptors. c. Blockade of norepinephrine receptors. d. Blockade of serotonin receptors. e. Blockade of monoamine oxidase. Which one of the following statements best describes the concept of randomization in a clinical trial. Select one: a. All subjects are assigned to the different groups by chance. b. Subjects are assigned to groups based on birth dates. c. Subjects are assigned to groups based on expected outcomes or success. d. Subjects are assigned to groups based on the severity of disease. e. Subjects are assigned to groups based on the order in which they arrive in the clinic. Which one of the following can increase the central nervous system depression induced by ethyl alcohol. Select one: a. Food. b. low doses of cocaine c. Caffeine. d. Other CNS depressants. e. Epinephrine. The primary transmitter at all autonomic ganglia is: Select one: a. Epinephrine. b. Serotonin. c. Norepinephri
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