Question

1) In eukaryotes, pyruvate is further metabolized via three main catabolic pathways. Circle the following correct statements

I. Under anaerobic conditions, pyruvate is oxidized leading to the formation of acetyl-CoA and CO2

II. Under aerobic conditions, pyruvate is oxidized leading to the formation of acetyl-CoA and CO2

III. Pyruvate can be reduced to lactate and CO2 during lactic fermentation

IV. Pyruvate can be reduced to ethanol and CO2 during alcoholic fermentation

V. Lactate produced by muscles from pyruvate is converted to glucose in the liver

VI. Lactate produced by the liver from pyruvate is converted to glucose in muscles