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11. In which of the following patterns of inheritance, the affected individual certainly has at least one affected parent?

A.

XLR, when a male is affected
B.

AD when the affected individual is the proband.
C.

XLD with incomplete penetrance
D.

XLR in a homozygous recessive female
E.

AR traits
F.

Two of the above

12. John has Vitamin D-resistance Rickets (XLD with 100% penetrance). Sue is pregnant and has Dentinogenesisimperfecta (AD with 80% penetrance). What is the chance that the child will be normal for both conditions? Both of the traits are rare in the corresponding population.

A.

Zero
B.

30%
C.

40%
D.

55%
E.

100%

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Jean Keeling
Jean KeelingLv2
30 Apr 2019
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Related questions

16. Assume that you don't have any information about an individual's parents or offspring. In which of the following, you CANNOT determine the genotype of the individual from his/her phenotype directly and with certainty?

A.

An unaffected individual in an XLD pedigree with complete penetrance
B.

An individual who displays the recessive phenotype of a Mendelian trait
C.

An individual with curly hair (Incomplete dominance)
D.

An affected male with red-green color blindness (XLR)
E.

An affected male with a Y-linked trait
F.

An unaffected teenage child of an affected individual with Huntington (AD), in a population with complete penetrance of this disorder
G.

An unaffected individual who has an affected parent and an affected child in a pedigree with incomplete penetrance

17. John and his maternal uncle both are affected with a cytoplasmic (mitochondrial) trait. John’s mother has passed away. Which of the following is (are) WRONG? Find the best answer.

A.

John’s mother was affected, and transmitted the trait to John.
B.

John’s maternal grandmother was affected
C.

John’s maternal aunt should be affected
D.

All of John’s sibs should be affected
E.

There is no chance for any of John's nephews to be affected.

1. Neurofibromatosis is inherited as a dominant gene. If a young child is the first in her family to be diagnosed (the proband), and the disease has a full penetrance in the corresponding population, which of the following is correct?

A. The mother is the carrier of the allele

B. The mutation has occured in gametogenesis of one of the parents

C. The condition will skip some generations in the family

D.

The child will certainly have normal siblings with the abnormal genotype.
E.

Both parents cannot be free from the disorder- one of them will certainly display the symptoms later in life.

F. Either infidelity is involved, or the child is not the biological offspring of her parents.

2. A man who suffers from a Y-linked disease marries a normal woman who has a red-green color blind (XLR) maternal grandfather. What is the chance that the couple will have a child affected with both conditions?

A.

Zero
B.

25%
C.

50%
D.

12.5%
E.

100%

***Just need the answer for #10 - 8 & 9 included for more info***

8- A Martian creature called a gazook has 17 pairs of chromosomes. Three genes for three traits are considered: eyeball gene with two alleles, round and square (R, r); tail gene with two alleles, hairy and smooth (H, h); and toe gene with two alleles, 9 toes and 11 toes (T, t). Round eyeballs, hairy tails and 9 toes are dominant to square eyeballs, smooth tail and 11 toes. A male has offspring with a gorgeous female who has square eyeballs, a hairy tail and 9 toes on each of her three feet! She gives birth to 200 little gazooks, who have the following phenotypes: - 100 have round eyeballs, 100 have square eyeballs - 100 have hairy tails, and 100 have smooth tails - 150 have 9 toes, and 50 have 11 toes What is the chance that in the future, this couple will have an offspring who is not phenotypically identical to either of the parents? Hint: Calculate the chance for the offspring to be phenotypically identical to either of the parents, then subtract it from 100%. A- 12.5% B- 25% C- 50% D- 62.5% E- 75% F- 87.5%

9- In the question above, what is the chance that this couple (couple A) will have a child, who is a boy, genotypically identical to one of the parents (mom or dad), and a child, who is a girl phenotypically identical to one of the parents (mom or dad)?

A- 3/16 chance for the girl, and 1/8 chance for the boy

B- 1/4 chance for both

C- 1/2 chance for the girl, and ½ chance for the boy

D- 1/8 chance for the girl, and 3/16 chance for the boy

E- 1/8 chance for the girl, and 3/8 chance for the boy

F- 1/16 chance for both

10- In the scenario above, another couple (couple B) and their 200 little gazooks move in the next door house. All the little gazooks are phenotypically identical to their father. The female is a supermodel who has square eyeballs, a smooth tail, and 11 toes on each of her three feet, and the male has round eyeballs, a hairy tail, and 9 toes. One year later, both Mrs. A and Mrs. B get pregnant, and each one gives rise to 200 new gazooks in the following year. The new children of couple A, all have round eyeballs, hairy tails, and 9 toes. Some of the new children of couple B have square eyeballs, smooth tails and 11 toes. What is the genotype of Mr. B, and which of the following is true?

A- Mr. B is ‘RrHHTT’, and he did not have an affair with Mrs. A

B- Mr. B is ‘RRHHTT’, and he had an affair with Mrs. A.

C- Mr. B is ‘RRHHTT’, and Mr. A had an affair with Mrs. B.

D- Mr. B is ‘RRHHTt’, and he had an affair with Mrs. A.

E- Mr. B is ‘RRHHTt’, and both Mrs. A and Mrs. B have some explaining to do because of the night they spent in a bar when both Mr. A and Mr. B had gone to a bachelor party together.

F- B and C are correct

G- D and E are correct

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