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MBLG2972 (21)

Class Notes for MBLG2972 at University of Sydney

Genetics and Genomics (Advanced)

MBLG2972 Lecture Notes - Lecture 21: Chromatin, Genomic Imprinting, Chromosome
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MBLG2072 Genetics and Genomics Monica Zanuttini 460381099 Functional genomics and epigenetics: Dierentiation of cells to dierent functions: due to functional genomics and epigenetics. Cells have had a dierent developmental...

Microbiology
MBLG2972
Professor Mary B
MBLG2972 Lecture Notes - Lecture 16: P1 Phage, Prophage, Lambda Phage
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MBLG2072 Genetics and Genomics Monica Zanuttini 460381099 Lecture 16 Bacterial gene transfer Bacteriophage life cycles: <1 of the size of bacteria. Icosahedral head, hollow protein sheath, some have tail bers. Single chrom...

Microbiology
MBLG2972
Professor Mary B
MBLG2972 Lecture Notes - Lecture 19: Cytoskeleton, Morphogen, Syncytium
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MBLG2072 Genetics and Genomics Monica Zanuttini 460381099 Lecture 19 Developmental genetics How are cells organised into a coherent body plan during development? Transcription factors: involved in converting DNA into RNA, ...

Microbiology
MBLG2972
Professor Mary B
MBLG2972 Lecture Notes - Lecture 15: Karyotype, Antimicrobial Resistance, Hfr Cell
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MBLG2072 Genetics and Genomics Monica Zanuttini 460381099 Lecture 15 Bacterial gene transfer Plasmids: Covalently closed circles. F Plasmid (fertility): contains transfer genes. Oneway transfer from donors to recipients. F...

Microbiology
MBLG2972
Professor Mary B
MBLG2972 Lecture Notes - Lecture 13: Dna Replication, Covalent Bond, Amine
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MBLG2072 Genetics and Genomics Monica Zanuttini 460381099 Lecture 13 Mutation and repair Mutations (eect) and polymorphisms (no eect) can occur in every generation. Humans acquire one to four new mutations each generation ...

Microbiology
MBLG2972
Professor Mary B
MBLG2972 Lecture Notes - Lecture 17: Phenotypic Plasticity, Cell Cycle, Meiosis
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MBLG2072 Genetics and Genomics Monica Zanuttini 460381099 Lecture 17 Cytogenetics Downsyndrome = trisomy of chromosome 21. Chromosome 21 is the smallest human autosome, with 48 million nucleotides representing about 1.5 pe...

Microbiology
MBLG2972
Professor Mary B
MBLG2972 Lecture Notes - Lecture 14: Karyotype, P Element, Reverse Transcriptase
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MBLG2072 Genetics and Genomics Monica Zanuttini 460381099 Lecture 14 Mobile genetic elements Transposable genetic elements: Many forms, lengths, copy numbers, move via transposition. Can cause a mutation via insertional in...

Microbiology
MBLG2972
Professor Mary B
MBLG2972 Lecture Notes - Lecture 18: Gene Duplication, Color Blindness, Angiogenesis Inhibitor
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MBLG2072 Genetics and Genomics Monica Zanuttini 460381099 Lecture 18 Cytogenetics In animals, embryonic aneuploids have reduced viability. Inviability can result from: 1. Expression of deleterious recessives. 2. Imbalance ...

Microbiology
MBLG2972
Professor Mary B
MBLG2972 Lecture Notes - Lecture 20: Polyploid, Synthetic Biology, Hoxa11
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MBLG2072 Genetics and Genomics Monica Zanuttini 460381099 Lecture 20 Developmental genetics Amount of protein binding to enhancer element, is critical to having tight zones of dierentiation. These end up giving us dierenti...

Microbiology
MBLG2972
Professor Mary B
MBLG2972 Lecture Notes - Lecture 11: Quantitative Genetics, Heritability, Phenotype
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MBLG2072 Genetics and Genomics Monica Zanuttini 460381099 Lecture 11 Quantitative and quantitative genetics Qualitative traits: Controlled by a few genes of large eect. Phenotype can be determined by simple crossing experi...

Microbiology
MBLG2972
Professor Mary B
MBLG2972 Lecture Notes - Lecture 12: Behavioural Genetics, Vasopressin Receptor 1A, Wild Type
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MBLG2072 Genetics and Genomics Monica Zanuttini 460381099 Lecture 12 Mapping of a heritable trait: 1. QTL mapping: We start with two strains that dier strongly in the trait of interest (a saturated genetic map i.e. has a r...

Microbiology
MBLG2972
Professor Mary B
MBLG2972 Lecture Notes - Lecture 2: Hbb, Domestic Pigeon, Type I Collagen
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MBLG2072 Genetics and Genomics Monica Zanuttini 460381099 Lecture 2 Dihybrid cross: Cross between individuals diering in two characters. Mendels second law or the law of independent assortment: During gamete formation segr...

Microbiology
MBLG2972
Professor Mary B
MBLG2972 Lecture Notes - Lecture 3: Glutamine, Human Height, Lethal Allele
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MBLG2072 Genetics and Genomics Monica Zanuttini 460381099 Lecture 3 Allelic series: Diploid organisms have two alleles at each locus. An order of dominance between alleles can from an allelic series. Autosomal Recessive In...

Microbiology
MBLG2972
Professor Mary B
MBLG2972 Lecture Notes - Lecture 6: Mendelian Inheritance, Centimorgan, Genetic Distance
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MBLG2072 Genetics and Genomics Monica Zanuttini 460381099 Lecture 6 Linkage and gene...

Microbiology
MBLG2972
Professor Mary B
MBLG2972 Lecture Notes - Lecture 4: Melanin, Anthocyanin, Meristem
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MBLG2072 Genetics and Genomics Monica Zanuttini 460381099 Lecture 4 Factors aecting observe...

Microbiology
MBLG2972
Professor Mary B

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